Sexual side effects from SSRI's (Full Version)

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Aneirin -> Sexual side effects from SSRI's (7/22/2007 4:00:54 PM)

I know one of the most common side effects from people taking SSRI's,is sexual disfunction.The question I have is how long does this last,is it a short term thing or can it go on for the duration of the treatment?Does anyone have any experience of this side sffect?




Phin -> RE: Sexual side effects from SSRI's (7/22/2007 5:04:44 PM)

I am currently taking two SSRIs and I have had no noticable side effects. The newer ones were formulated with thought given to side effects




nyrisa -> RE: Sexual side effects from SSRI's (7/22/2007 9:10:11 PM)

Wellbutrin did not diminish my sex drive; as a matter of fact, I think it enhanced it. I have found that zoloft and cymbalta both decreased my sexual interest, although I know another young woman on zoloft who has had no decrease. She would have welcomed a decrease in interest, as her husband has a less active libido, and she is often sexually frustrated.




sweetnurseBBW -> RE: Sexual side effects from SSRI's (7/22/2007 9:15:13 PM)

SSRI's like meds  also known as Prozac, Zoloft, and Paxil can cause decreased libido and absence of orgasm. Some can cause in men the absence of ejaculation or unable to achieve erection. Not all persons on SSRI's cause this in every person. Best bet is to talk to your Doc if concerned about it,




Emperor1956 -> RE: Sexual side effects from SSRI's (7/22/2007 9:32:34 PM)

The LONG answer:   Sexual side effects with SSRIs are finally being studied in a systematic way, and the results are not encouraging.  When these drugs were first introduced, the rate of side effects was less than 10%, supposedly, but this was based on a self-reporting mechanism that was inherently unreliable.  Recent studies have stated a sexual side effect rate (based upon response to physician questioning) of 40% +  And one study found a rate of self-reported side effect as "bothersome" in 83% of patients studied! 

The most commonly reported side effect in both men and women is lessened libido.  An inability to orgasm is reported by both genders, but more so by women.  Men report impotence although no study has checked co-morbidity factors such as diabetes, heart disease, etc.  And of course persons with clinical depression often have depressed sexual feelings and responses.  Also, while generally these side effects clear up when the drug is discontinued, a significant minority of patients report continuing symptoms.

(AND NOTE:  Discontinuing SSRIs is NOT a simple "stop taking the pill" -- DO NOT EVER GO OFF an SSRI, or have a loved on go off a prescription, without physician supervision.  THERE, I've done my PSA for the day).

By the way, Buproprion (Wellbutirin) is not an SSRI.  It works on norepinephrine and dopamine systems in the brain, not seratonin.  Indeed, it is sometimes prescribed with an SSRI because it counters the tendency of SSRIs to result in decreased dopamine release in some patients, and dopamine is a precourser to sexual arousal.

The short answer:  This is serious medicine.  Don't play with it.  Talk to a knowledgeable MD and please do not take advice on medication from CollarMe...even from me.

E.





MisPandora -> RE: Sexual side effects from SSRI's (7/23/2007 3:38:26 AM)

quote:

ORIGINAL: Aneirin

I know one of the most common side effects from people taking SSRI's,is sexual disfunction.The question I have is how long does this last,is it a short term thing or can it go on for the duration of the treatment?Does anyone have any experience of this side sffect?

SSRIs do different things to different people, thus being under a physician's care for the need of titrating drugs to get the most out of the drug(s).  Each drug has a list of different "labeled side effects" that had to be documented by the company to the FDA when they released the drug onto the market.  They come with the drug from your pharmacist on something called a patient insert.  You can also find this information on the drug or drug company website, in the PDR (Physicians Desk Reference) or on a website called rxlist.com.  Most importantly, if you're having side effects, whether the insert says you should or not, TALK TO YOUR DOCTOR!




Devoura -> RE: Sexual side effects from SSRI's (7/23/2007 11:04:20 PM)

Everyone's experience is different. I agree that Wellbutrin greatly increased my sex drive, while Lexapro completely demolished it. For many, the side effects go away in a few weeks\months as your body becomes adjusted. For others, it takes years *after* going off of medication for their bodies to return to normal. Seconding finding a *good* doctor who will give you straight information, there are really horrible psychs out there. Good luck =)

~Dev




sexypet -> RE: Sexual side effects from SSRI's (7/23/2007 11:06:37 PM)

About 10 yrs ago, i was on prozac.  My sex drive was crushed.  About 10 days after i discontinued it, all i wanted to do was fuck all day, and still do today.  [:D]




Emperor1956 -> RE: Sexual side effects from SSRI's (7/25/2007 8:25:54 AM)

Nice to see you again, Pandora




camille65 -> RE: Sexual side effects from SSRI's (7/25/2007 9:49:43 AM)

quote:

ORIGINAL: Aneirin

I know one of the most common side effects from people taking SSRI's,is sexual disfunction.The question I have is how long does this last,is it a short term thing or can it go on for the duration of the treatment?Does anyone have any experience of this side sffect?


I've been on 150mg Zoloft for nearly 5 years and my libido is RIP dead dead. It is really strange because there is simply no arousal and most definitely no orgasming but it (sexuality) is so remote due to the meds it nearly doesn't matter.

Since I'm not in daily contact with my dom it hasn't been much of an issue, but yesterday I brought up changing meds to my doctor.

After reading Emperors post I'm going to ask that I try wellbutrin in conjunction with the Zoloft. It is time for me to be a sexual being again dang it. Thanks Emperor for mentioning the possibility of combining the two!

I will repeat too what he said, please don't ever decide to drop or alter your meds without discussing it with your doctor first. I learnt firsthand that doing so is a very bad idea!

[sm=goodnight.gif]  (my libido, may she rest in peace)




GrizzledMaster -> RE: Sexual side effects from SSRI's (7/25/2007 8:07:09 PM)

Good information, Emperor. I agree wholeheartedly.  The most important thing to find is a good psychiatrist who is comfortable talking about sexual problems with you and will help you find the right med for YOU!

Remember psychiatrists and doctors are like everyone else, they find something they like and stick with it. It is really is up to you to give him the feedback to treat you properly.




Aswad -> RE: Sexual side effects from SSRI's (7/26/2007 12:10:04 AM)

Aneirin,

It can last anywhere from never to forever. You'll need to be more specific as to what experiences you are looking for feedback on, as there is much ground to cover. Also, more background on the situation would be good, like whether you've started and are asking about stuff you're experiencing now, or are just curious about what might come to pass in terms of side-effects, or whether it's someone else, etc.

If it's for depression, you could ask your doctor to consider something more neutral, like moclobemide (Aurorix, Manerix), or something with more positive effects, like bupropion (Wellbutrin, Zyban).

Usually, though, it's mostly short-term, or otherwise manageable.
Usually, the docs are also clueless about the latter, in my experience. YMMV.




Aswad -> RE: Sexual side effects from SSRI's (7/26/2007 12:15:32 AM)

quote:

ORIGINAL: Phin

I am currently taking two SSRIs and I have had no noticable side effects.


Just curious about why this is?
Combining SSRIs rarely makes sense.
Adding other things to an SSRI is common.

quote:


The newer ones were formulated with thought given to side effects


No. Not at all. And newer drugs are less frequently SSRIs.

Perhaps one of them is escitalopram (Lexapro, Cipralex) or citalopram (Celexa, Cipramil)?
That one cannot reach the same level of reuptake inhibition as the others.
It is also very selective for one receptor type.

This accounts for its low efficacy and few side-effects; it does less.
But sometimes, that is more useful, depending on the problem.




Aswad -> RE: Sexual side effects from SSRI's (7/26/2007 12:19:33 AM)

quote:

ORIGINAL: nyrisa

Wellbutrin did not diminish my sex drive; as a matter of fact, I think it enhanced it. I have found that zoloft and cymbalta both decreased my sexual interest, although I know another young woman on zoloft who has had no decrease. She would have welcomed a decrease in interest, as her husband has a less active libido, and she is often sexually frustrated.


Wellbutrin is not an SSRI, it is a catecholamine reuptake inhibitor.
Cymbalta is not an SSRI, it is principally a serotonin-norepinephrine reuptake inhibitor.
Zoloft is an SSRI, though some have suggested it may be a serotonin-dopamine reuptake inhibitor instead.

Anything that increases serotonin or decreases dopamine can mess up your sex life.

Intrinsa is becoming a common remedy.
Wellbutrin is a common band-aid.
Better doctors are a cure.




Aswad -> RE: Sexual side effects from SSRI's (7/26/2007 12:26:31 AM)

quote:

ORIGINAL: camille65

After reading Emperors post I'm going to ask that I try wellbutrin in conjunction with the Zoloft. It is time for me to be a sexual being again dang it. Thanks Emperor for mentioning the possibility of combining the two!


I thought I mentioned that to you the last time you asked? [:D]

There are a lot of options to try, including testosterone (Intrinsa), cabergoline (Cabaser), amineptine (Survector), tianeptine (Stablon), bupropion (Wellbutrin), and various others. Most of these also augment the antidepressant response. A failed tanning cream with the "nasty" side-effect of causing arousal is also on its way, but the name escapes me right now.

Bupropion is not the best choice, IMO, but it is the most common one, despite the lack of quality studies.




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