samboct -> RE: HPV (10/24/2011 6:22:04 AM)
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DeviantlyD There is a push to vaccinate young people before they can get infected with various strains of HPV, since as once you've been infected, with the strain found in the vaccine- the vaccine doesn't do a whole lot of good. So your clarification is helpful- mea culpa for writing something potentially confusing. The vaccine costs several hundred dollars so there's an economic reason to deny access to the vaccine, which is why it's being pushed for youngsters where it's certainly going to do some good. Due to the economics, some physicians may be reluctant to prescribe the vaccine for women who have been sexually active. I think its unusual (unknown?) for HPV to infect with multiple strains at the same time. Yes, you can get different viruses at the same time, but I'm pretty sure that its quite unlikely to get infected with say HPV strain 16 at the same time as HPV strain 54. If I understand this correctly, you can have multiple antibodies for various viral strains which is how science shows you've been infected, but the infections have to occur sequentially for HPV. Note- I'm not a virologist, so this is something I need to check on, but I know for diseases like dengue- you get one strain at a time, and the second dengue infection is highly problematic. There are viruses such as HCMV where it is possible to get a mixed infection of several strains simultaneously. There's also another issue here- and one that's been a political hot potato. HPV infection doesn't automatically lead to cervical cancer, although some form of HPV infection is found in most (possibly all?) cases of cervical cancer. However, it's been known for decades that sex with multiple partners increases the risk of cervical cancer. There's probably been some racial overtones here as well, with women of a lower socio-economic class (i.e. poor) engaging in sex with multiple partners more frequently than women from higher socio-economic levels. It's NOT just sexual frequency- they did the control study with single partners. Somehow sex with multiple partners depresses the immune system so that HPV infection progresses to cancer. This is where the politics comes in- why should youngsters who may have few sexual partners in their life get treated with a vaccine for a disease that they're very unlikely to get? Women with a stronger immune system clear HPV infection with no need for a vaccine most of the time. The Pap smear is one of the few success stories in cancer diagnostics- the problem with it is that it needs a well trained individual using a microscope to determine whether or not the cells are progressing towards cancer. These vaccines make more sense in developing world countries, but they're unaffordable. Sam
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